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Updated: Jun 30, 2025

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基因组多样性和Mycobacterium simiae的临床相关性

Nils Wetzstein1,2,3, Margo Diricks2,3, Sönke Andres4

  • 1Goethe University Frankfurt, University Hospital, Department of Internal Medicine, Infectious Diseases, Frankfurt am Main, Germany.

ERJ open research
|March 19, 2024
PubMed
概括

菌根菌的感染很少见,通常具有较低的临床意义. 基因组分析显示,患者体内的细菌种群稳定,尽管菌株之间存在遗传相似性,但人对人传播不太可能.

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Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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