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Kensaku Yoshida¹, Mikio Nakajima², Richard H Kaszynski³

¹Neurological Surgery, Tokyo Metropolitan Hiroo Hospital, Tokyo, JPN.

|March 19, 2024

概括

在头部CT扫描中,基底质的低密度病变与COVID-19患者的更高的死亡率和更长的住院时间有关. 这些发现表明,基底腺缺血变化可以作为一个关键的预后指标.

科学领域:

神经学神经学
放射学放射学是一门学科.
传染性疾病传染性疾病

背景情况:

COVID-19可能会影响大脑,神经系统并发症会影响患者的治疗结果.
头部计算机断层扫描 (CT) 用于评估COVID-19患者的神经变化.
基底腺是关键的大脑区域,通常在头部CT扫描中进行评估.

研究的目的:

调查头部CT检测结果,特别是基底质中低密度病变与COVID-19患者的死亡率之间的联系.
为了确定基底质低密度病变是否预测COVID-19患者的住院死亡率和住院时间.

主要方法:

在东京大都会希鲁医院 (1-2021年1月至12月) 的1203名COVID-19住院患者进行了回顾性队列研究.
患者根据头部CT基底质中低密度病变的存在或不存在来对患者进行分类.
使用多变量回归分析来评估基底瘤病变与结果之间的关联,并根据患者特征和疾病严重程度进行调整.

主要成果:

在一小部分COVID-19患者中发现了基底质中低密度的病变.
多变量分析显示,基底质低密度病变与增加住院死亡率之间存在显著的关联.
这些病变的存在也与长时间住院相关.

结论:

基底质中低密度的病变,表明缺血变化,是COVID-19患者的显著预后因素.
基底质中头部CT发现可能有助于预测临床结果和指导患者管理.

关键词:

基底性腺 (Basal Ganglia) 是一个大脑梗塞脑梗塞大脑小血管疾病是大脑小血管疾病.在COVID-19中,有很多人.这是一个CT检测.低密度病变的病变密度较低.

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