帕金森病研究中的全球生物标志物趋势:图书统计分析
Xingxin Wang1, Tiantian Dong1, Xuhao Li1
1School of Acupuncture-Moxibustion and Tuina, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.
Heliyon
|March 19, 2024
概括
图书统计分析揭示了帕金森病 (PD) 生物标志物研究的关键趋势. 未来的方向包括外体,miRNA和机器学习,用于早期诊断和了解PD病理学.
科学领域:
- 神经科学和神经病学 神经科学和神经病学
- 生物标志物发现发现
- 图书统计学 图书统计学
背景情况:
- 帕金森病 (PD) 是一种流行的神经退行性疾病,影响全球数百万人.
- 对PD生物标志物的研究正在迅速扩大,这是由于需要了解其复杂的病理生理学而推动的.
- 现有的研究突出了生物标志物开发的各个阶段,从探索到多模式方法.
研究的目的:
- 为了对帕金森病生物标志物研究进行参考资料分析.
- 确定关键的科学概念,新兴趋势和全球研究发展模式.
- 绘制PD生物标志物研究的地图,包括主要期刊,作者,机构和研究方向.
主要方法:
- 使用各种工具进行图书统计分析.
- 确定关键的科学概念和新兴趋势.
- 分析出版物产出,引用,合作和研究方向.
主要成果:
- 运动障碍是PD生物标志物研究的领先期刊.
- 确定了主要作者 (例如,莫伦豪尔,塞勒姆) 和机构 (例如,宾夕法尼亚大学,美国).
- 神经科学是主要的研究领域,主要关注α-synuclein,神经递质,炎症,氧化应激和神经成像生物标志物.
结论:
- 未来的帕金森病生物标志物研究可能将集中在外体,血生物标志物,miRNA,脑脊液,机器学习和动物模型上.
- 这些进展对于改善早期诊断,监测疾病进展和阐明PD的病理机制至关重要.
- 该研究提供了对PD生物标志物研究当前状态和未来轨迹的全面概述.
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