在患有阻塞性睡眠呼吸暂停的高血压患者中,症状和并发症负担
MengShi Tao1,2, Xiaoqi Dong1, Jinjing Tu1
1Department of Respiratory and Critical Care Medicine, The Affiliated Lihuili Hospital of Ningbo University, Ningbo, China.
Frontiers in endocrinology
|March 19, 2024
概括
阻塞性睡眠呼吸暂停 (OSA) 患有高血压的患者年龄较大,体重指数较高,并且经历更多的白天嗜睡和夜尿. 他们还面临糖尿病,心脏病和中风的风险增加.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 睡眠医学 睡眠医学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是高血压 (HTN) 的重要,但往往未被认可的危险因素.
- 在OSA患者中,高血压的患病率很高,但不同的临床特征和并发症需要进一步定义.
- 了解这些差异对于管理OSA及其相关心血管风险至关重要.
研究的目的:
- 为了比较患有高血压和没有高血压的OSA患者之间的临床症状和并发症.
- 在被诊断为OSA的患者中确定高血压的独立风险因素.
- 为了阐明OSA严重程度和高血压状态之间的关系.
主要方法:
- 从2016年至2020年,对1108名新诊断的OSA患者进行了回顾性分析.
- 患者分为患有高血压的OSA (n=387) 和没有高血压的OSA (n=721) 组.
- 对社会人口统计数据,临床症状,并发病症和多睡眠学结果进行比较;进行多变量分析.
主要成果:
- 患有高血压的OSA患者年龄较大,体重指数和爱普沃思睡眠分数 (ESS) 更高.
- 在高血压OSA组中观察到夜尿,糖尿病,冠心病和脑血管疾病的发病率增加.
- 在OSA中HTN的独立风险因素包括年龄,BMI,ESS,夜尿,糖尿病,冠心病和缺血性中风.
结论:
- 与没有高血压的患者相比,患有高血压的OSA患者在白天表现出更大的睡眠和夜.
- 在OSA中,高血压与伴随疾病的风险显著增加,包括糖尿病,冠状动脉心脏病和脑血管疾病.
- 这些发现强调了OSA和高血压之间的关键联系,强调了需要综合管理策略的必要性.
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