COVID-19:对辅助生殖安全的挑战
Marise Samama1, Frida Entezami2, Daniela S Rosa3
1Department of Gynecology, Federal University of São Paulo, São Paulo, Brazil; GERA Institute of Reproductive Medicine, São Paulo, Brazil.
Sleep medicine clinics
|March 19, 2024
概括
在COVID-19期间的辅助生殖技术 (ART) 增加了怀孕风险. 本综述详细介绍了生育治疗的风险和安全管理策略,重点关注激素和手术程序.
科学领域:
- 生殖医学和免疫学
背景情况:
- 随着COVID-19大流行,接受辅助生殖技术 (ART) 的人面临重大风险.
- SARS-CoV-2 感染可能会影响生育能力和怀孕结果,特别是在患有先前疾病的患者中.
- 了解COVID-19和泌尿器官系统之间的相互作用对于生育管理至关重要.
研究的目的:
- 在COVID-19大流行期间审查现有关于生育治疗相关风险的文献.
- 概述策略,以减轻荷尔蒙和手术ART程序的潜在并发症.
- 为了应对SARS-CoV-2在接受ART的前症状不育患者中所带来的挑战.
主要方法:
- 在PubMed中对2020年1月至2022年7月期间发表的研究进行了全面的文献搜索.
- 关键词包括COVID-19,SARS-CoV-2,怀孕,生育,辅助人类生殖,受控卵巢刺激,体外受精,激素和外科手术.
- 分析了关于怀孕结果,泌尿器官系统相互作用和免疫/原血栓状况的数据.
主要成果:
- COVID-19患者表现出改变的免疫和原血栓状况,在ART期间增加风险.
- 控制性卵巢刺激 (COS) 和ART手术可能会通过增强细胞因子风暴来加剧COVID-19的严重程度.
- 前症状的SARS-CoV-2感染对ART中的荷尔蒙,免疫和前血栓风险管理构成挑战.
结论:
- 在COVID-19大流行期间的ART程序需要仔细评估风险和管理策略.
- 减轻荷尔蒙,免疫和前血栓风险对于患者的安全至关重要.
- 开发安全的ART协议对于预防病毒爆发期间不育患者的并发症至关重要.
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