在接受过导管动脉化学栓塞治疗的原发性肝癌患者中,症状群和营养状况
Jianfeng Zhang1, Hongyan Duan2, Jie Zhang3
1Wuxi School of Medicine. Jiangnan University.
Nutricion hospitalaria
|March 19, 2024
概括
接受TACE的原发性肝癌患者经常出现营养不良,这与症状集群增加有关. 识别这些症状集群和营养状况对于患者护理至关重要.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 临床营养学 临床营养学
背景情况:
- 症状集群 (SCs) 在原发性肝癌中很常见.
- 营养不良加剧了这些患者的症状严重程度.
- 过导管动脉化学栓塞 (TACE) 是肝癌的常见治疗方法.
研究的目的:
- 在接受TACE的原发性肝癌患者中确定SCs.
- 评估这些患者的营养状况.
- 调查营养状况和SCs之间的关联.
主要方法:
- 探索性因子分析用于SC识别.
- 使用NRS-2002和血液生物化学进行营养评估.
- 斯皮尔曼相关性用于评估营养状况和SCs之间的关系.
主要成果:
- 确定了四种不同的SCs:情绪-心理,上部胃肠道,栓塞后和肝功能障碍.
- 68.14%的患者有营养不良的高风险.
- 在营养不良和营养良好患者之间观察到SC得分的显著差异,营养不良风险 (NRS-2002) 和SC得分之间存在正相关性,与前白蛋白水平有负相关性.
结论:
- 接受TACE治疗的肝癌患者面临营养不良的高风险.
- 营养不良与症状集群严重程度的增加有关.
- 营养状况评估对于管理这些患者的症状负担至关重要.
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