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Updated: Jun 30, 2025

Cycloheximide Chase Analysis of Protein Degradation in Saccharomyces cerevisiae
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Published on: April 18, 2016

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对Clp蛋白质降解机制的结构见解

Xiaolong Xu1,2, Yanhui Wang1,2, Wei Huang1,2

  • 1Department of Neurosurgery, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China.

mBio
|March 19, 2024
PubMed
概括

细菌中的Clp蛋白酶系统对于蛋白质稳态至关重要,它涉及ClpP蛋白酶和Clp-ATP酶. 这项研究揭示了Streptomyces hawaiiensis ClpC1:shClpP1P2复合物的结构,详细介绍了相互作用和基质转位机制.

关键词:
在AAA+ ATPase中.在ADEP1中,它是ADEP1.在ClpP蛋白酶中,蛋白质降解 蛋白质降解基板转位机制 基板转位机制

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