急性中毒的重症监护管理,随时间变化的动态和变化:一个队列研究
Alexander Christian Reisinger1, Nikolaus Schneider1, Nikolaus Schreiber1
1Department of Internal Medicine, Intensive Care Unit, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria.
Internal and emergency medicine
|March 19, 2024
概括
这项研究分析了2007-2021年期间在重症监护室 (ICU) 中发生的急性中毒病例. 尽管精神疾病增加,但随着时间的推移,中毒患者的ICU死亡率仍然很低.
科学领域:
- 毒理学 毒理学 毒理学
- 临界护理医学 临界护理医学
- 公共卫生 公共卫生
背景情况:
- 急性中毒和中毒是重症监护室 (ICU) 入院的重要原因.
- 了解患者的特征和结果对于改善护理至关重要.
- 毒害病例的时间趋势和管理策略需要调查.
研究的目的:
- 描述2007年至2021年期间因急性中毒而入院医疗ICU的患者.
- 为了确定与中毒患者的ICU死亡率相关的因素.
- 将当前发现与历史队列 (1992-1996) 进行比较,以评估随时间的变化.
主要方法:
- 对2007-2021年期间因急性中毒而入院的成年ICU患者的回顾性数据分析.
- 包括来自ICU,医院前,急诊室和尸检报告的数据.
- 探索性子分析,将当前数据与历史队列 (1992-1996) 的数据进行比较.
主要成果:
- 581例急性中毒病例进入ICU (2007-2021);女性45%,混合中毒46.6%.
- 主要原因是自杀意图 (48.2%);中位数的ICU停留时间为1.2天.
- 集中治疗室死亡率为4.1% (当前) 与4.2% (历史);先前存在的精神疾病从49%增加到69%.
结论:
- 对于急性中毒的ICU死亡率仍然很低,并且随着时间的推移而保持稳定.
- 在被中毒的ICU患者中,先前存在的精神疾病的显著增加表明需要加强预防.
- 治疗趋势显示,人们正在从胃洗转向替代性排毒方法.
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