意识障碍患者的部肌肉动:一个试点研究
Valeria Pingue1, Marta Mirando2,3, Benedetta Cazzulani4
1Neurorehabilitation and Spinal Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy - valeria.pingue@icsmaugeri.it.
European journal of physical and rehabilitation medicine
|March 19, 2024
概括
部肌肉性在意识障碍 (DOC) 患者中很常见,特别是在创伤性脑损伤后. 在不响应性清醒综合征 (UWS) 中,严重的动预示着较差的结果,指导康复目标.
科学领域:
- 神经科学是一个神经科学.
- 康复医学 康复医学 康复医学
- 临床神经学 临床神经学
背景情况:
- 意识障碍 (DOC) 包括昏迷,不响应的清醒综合征 (UWS) 和严重获得性脑损伤 (ABI) 后的最小意识状态 (MCS).
- 性是DOC患者经常出现的并发症,但性特定的研究和治疗仍然有限.
- 这项试点研究解决了在DOC中对椎脊柱肌肉动的集中评估的需要.
研究的目的:
- 在大量成年DOC患者中评估部肌肉性.
- 调查性对ABI后6个月的神经和功能结果的影响.
- 探索在不同DOC状态下部的危险因素和临床相关性.
主要方法:
- 一个单一中心的前性试点研究,涉及严重ABI和DOC的患者.
- 数据收集包括人口统计,ABI病因,DOC分类 (使用CRS-R) 和结果 (GCS,FIM).
- 评估了宫动 (MAS),头部对齐 (goniometer) 和疼痛 (NCS-R).
主要成果:
- 48名DOC患者中有91.7%的部肌肉,UWS和MCS之间严重程度没有显著差异.
- 在创伤性脑损伤 (TBI) 病例中,性比较严重. 年轻的年龄,半综合征和四度预测了MCS中的性严重程度.
- 在UWS患者中,较大的性严重程度与出院时更差的神经和功能结果相关.
结论:
- 部肌肉性在DOC中非常普遍,在TBI后更严重.
- 在UWS和MCS之间,关于风险因素和结果的性概况有所不同.
- 在UWS中部的严重程度可能成为康复结果的早期预测因素.
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