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Updated: Jun 30, 2025

Induction and Assessment of Class Switch Recombination in Purified Murine B Cells
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Induction and Assessment of Class Switch Recombination in Purified Murine B Cells

Published on: August 13, 2010

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人类B细胞内存中的同型切换设置了内在的抗原-亲和度值,这决定了抗原驱动的命运

Abhijit A Ambegaonkar1, Prasida Holla1, Haewon Sohn1

  • 1Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD 20852.

Proceedings of the National Academy of Sciences of the United States of America
|March 19, 2024
PubMed
概括

人体内存B细胞 (MBCs) 具有不同的作用. IgG+ MBCs产生抗体,而IgM+ MBCs通过生殖中心反应产生新的抗体多样性,增强免疫记忆.

关键词:
在B细胞受体同型.亲缘关系的门值.记忆 B 细胞 B 细胞

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