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Updated: Jun 30, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
07:30

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Published on: January 21, 2020

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通过来自Bacillus tequilensis的酸还原酶启动的药学相关的阿里胺的合成

Sara Russo1,2, Alejandro Prats Luján1, Marco W Fraaije2

  • 1Department of Chemical and Pharmaceutical Biology, Groningen Research Institute of Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands.

Chembiochem : a European journal of chemical biology
|March 19, 2024
PubMed
概括

一种新型的酶,Bacillus tequilensis 缩酶 (BtNR),提供了一种可持续的方法来生产对药品至关重要的亚兰胺. 这种生物催化剂实现了高的转化率,为传统化学合成提供了一个环保的替代方案.

关键词:
亚里胺是一种胺.生物催化剂的生物催化剂黄蛋白是一种黄蛋白.亚降解酶的使用方法

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