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在全身麻醉下在人类中引起三角子宫反射的可行性和技术方面

Denise Lima Medeiros de Melo¹, Enio Alberto Comerlato¹, Denise Spinola Pinheiro²

¹Department of Clinical Neurophysiology. SARAH Network of Rehabilitation Hospitals, Brasília, DF, Brazil.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

|March 19, 2024

概括

这项研究表明,在全身麻醉下,可以在人体中可靠地记录三角质 - 宫反射 (TCR) 组件,特别是使用更长时间的刺激持续时间,在硬骨肌的短延迟反应.

科学领域:

神经生理学神经生理学
手术监测手术监测

背景情况:

三角子宫反射 (TCR) 是一种有价值的神经生理反应.
在全身麻醉下对人类的诱导和评估仍然具有挑战性.
在神经外科手术期间优化手术内监测至关重要.

研究的目的:

为了研究在全身麻醉下在人类中引起TCR元件的可行性.
分析神经生理学方面,刺激模式和TCR的地形分布.
评估TCR在手术内神经生理学监测中的潜力.

主要方法:

对20名接受后或脊髓手术的参与者进行前性观察性研究.
同时记录TCR在骨肌 (SCM) 和梯形肌.
电刺激上轨道/下轨道神经,具有不同的刺激持续时间 (0.2-0.5毫秒和0.5-1.0毫秒) 和单/多脉冲模式.

主要成果:

TCR组件,主要是ipsilateralSCM中的短延迟响应,在手术内记录,成功率可变.
刺激持续时间较长 (0.5-1.0毫秒) 增强了在全身麻醉下引起TCR反应的效果.
在SCM中,短延迟TCR组件经常通过更长的刺激持续时间引起.

结论:

在SCM中诱导短延迟TCR组件在全身麻醉下使用更长的刺激持续时间 (0.5-1.0毫秒) 在人类中是可行的.
这项研究是第一个在全身麻醉下在人类中证明TCR诱导的研究.
这种神经生理学技术有可能优化脑干手术期间的手术内监测.

关键词:

大脑干的反射反应在手术期间进行神经生理学监测.三胞胎反射是三胞胎的反射.三胞胎 - 宫反射反应

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