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使用pectin/casein生物聚合物的提升玄米香精油微封装:通过D-最佳设计,控制释放建模和表征优化

Sarah Hamid¹, Naima Fadloun Oukil¹, Hamza Moussa²

¹Laboratoire de Biotechnologie Végétale et Ethnobotanique, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, 06000 Bejaia, Algeria.

International journal of biological macromolecules

|March 19, 2024

概括

使用生物聚合物优化香精油 (BEO) 的微封装产生了高效率 (93.10%). 这种优化过程为开发有效的食品和制药产品提供了有希望的战略.

科学领域:

食品科学与技术食品科学与技术
材料科学材料科学材料科学
化学工程是化学工程的重要组成部分.

背景情况:

香精油 (BEO) 具有宝贵的特性,但需要稳定才能有效应用.
微封装 (MEC) 是保护和输送生物活性化合物的关键技术.
复杂的联合化为基于生物聚合物的MEC提供了一种多功能方法.

研究的目的:

为了优化在生物聚合物矩阵内微封装白香精油 (BEO).
评估优化的BEO微囊 (BEO-MCs) 的效率,产量和特性.
评估开发的BEO-MCs的受控释放动力学和热稳定性.

主要方法:

使用D-最佳设计来优化微封装过程.
复杂的联合化技术用于将BEO封装在生物聚合物矩阵中.
鉴定包括ATR-FTIR,X-RD,SEM和TGA-DSC分析.
控制释放动力学是使用已建立的动力学模型来建模的.

主要成果:

最佳的微封装实现了高产量 (80.45%) 和效率 (93.10%).
描述证实了成功封装,平均颗粒大小为4.81微米.
TGA-DSC分析表明BEO-MCs具有良好的热稳定性.
在模拟的胃肠道条件下,R2=0.99和RMSE=1.56%的动态模型准确地描述了受控释放.

结论:

D-最佳设计成功优化了使用生物聚合物的BEO微封装.
开发的BEO-MC显示出出色的产量,效率,稳定性和受控释放性能.
这种优化的MEC方法为食品和制药行业提供了一个有前途的战略.

关键词:

复杂的联合化.D-最佳设计的设计.数学模型是一种数学模型.这就是Ocimum basilicum. 这就是为什么我会这样做.质素 (Pectin) 是一种可怕的物质.

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