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Updated: Jul 19, 2026

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
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在多发性髓瘤中使用Selinexor

Enrica Antonia Martino1, Ernesto Vigna1, Antonella Bruzzese1

  • 1Hematology Unit, Azienda Ospedaliera Annunziata, Cosenza, Italy.

Expert opinion on pharmacotherapy
|March 19, 2024
PubMed
概括

作为XPO1抑制剂的Selinexor在复发性/耐药性多发性骨髓瘤 (RRMM) 中表现有前途. 临床试验证明了其在组合疗法中的有效性,改善了具有挑战性疾病的患者的响应率和无进展生存率.

关键词:
在 MM MM MM MM 里面.这就是Selinexor.一个XPO1一个XPO1一个XPO1治疗疗法治疗疗法治疗疗法

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...