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在内血管腹腔大动脉动脉瘤修复前侧枝栓塞以防止II型内泄:一个前性的多中心研究
Tomoyuki Gentsu1, Masato Yamaguchi1, Koji Sasaki1
1Department of Diagnostic and Interventional Radiology, Kobe University Hospital, Kobe, 7-5-2 Kusunokicho, Chuo Ward, Kobe City, Hyogo 650-0017, Japan.
Diagnostic and interventional imaging
|March 19, 2024
概括
预防性跨导管动脉栓塞 (P-TAE) 有效地防止EVAR后的II型内泄漏. 这种安全的程序促进了早期动脉瘤囊缩,减少并发症和改善患者的治疗结果.
科学领域:
- 血管外科 血管外科
- 干预性放射学 干预性放射学
- 医疗器械技术 医疗器械技术
背景情况:
- 第二种类型的内腔漏洞是内血管腹腔大动脉瘤修复 (EVAR) 后的常见并发症.
- 持续的内泄漏会导致持续的动脉瘤囊扩张和破裂风险.
- 目前正在探索预防性策略以减轻这些风险.
研究的目的:
- 评估先发性透气管动脉栓塞 (P-TAE) 在预防EVAR后II型内泄漏的安全性和有效性.
- 评估P-TAE对动脉瘤囊动态和相关并发症的影响.
主要方法:
- 一个多中心,前性,单臂试验,涉及100名患有腹腔大动脉动脉瘤的患者.
- 在EVAR之前或期间,P-TAE在动脉侧枝上进行.
- 主要终点:在6个月后出现II型晚期内泄漏的发生率;次要终点:囊径变化,并发症,重新干预和死亡率.
主要成果:
- 在80.9%的目标大动脉侧分支中成功栓塞,没有严重的不良事件.
- 晚期II型内皮漏洞发病率在6个月后为8.9%.
- 在12个月 (55.3%) 观察到显著的动脉瘤囊收缩,在患有内泄漏的患者中收缩较少.
结论:
- P-TAE是一种安全有效的方法,用于预防EVAR后的II型内泄漏.
- 该程序与12个月的早期动脉瘤囊收缩有关.
- 在研究队列中没有报告重复干预或动脉瘤相关的死亡.
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