基于有序后勤回归分析,分析胃食道逆流病与焦虑和抑郁之间的相关性
Qian Li1, Hui Duan1, Qiong Wang2
1The Third People's Hospital of Chengdu, Chengdu, China.
Scientific reports
|March 20, 2024
概括
这项研究揭示了更高的焦虑和抑郁水平与胃食道逆流症 (GERD) 严重程度的增加之间存在显著联系. 研究结果表明,GERD对心理健康有影响,为受影响患者提供了潜在的干预措施.
科学领域:
- 胃肠病学 胃肠病学
- 精神病学是一个精神病学.
- 医学统计 医学统计
背景情况:
- 精神症状 (焦虑,抑郁) 和胃食道逆流之间确立的联系.
- 关于胃食道逆流病 (GERD) 的严重程度与焦虑和抑郁症的强度之间的确切关系的不确定性.
研究的目的:
- 调查GERD严重程度与焦虑和抑郁程度之间的相关性.
- 确定与不同程度的焦虑,抑郁和GERD相关的基线特征.
主要方法:
- 收集了来自518个人的24小时pH监测数据和基线患者信息.
- 使用医院焦虑和抑郁量表来评估心理健康.
- 使用R软件 (4.1.3版本) 和后勤回归模型分析数据.
主要成果:
- 在焦虑/抑郁症严重程度和24小时pH监测结果之间发现了显著的正相关性.
- 更高的焦虑水平与GERD发病率的增加有关 (轻度焦虑或2.64,中度至重度焦虑或6.84).
- 中度至重度抑郁 (OR 2.32),男性性别 (OR 2.29),BMI升高 (OR 1.07) 和年龄增加与更高的GERD患病率有关.
结论:
- 焦虑和抑郁症的严重程度增加与更严重的GERD相关.
- 这些发现支持了GERD的精神关系,并可能指导未来的心理或药理干预.
- 为GERD患者具有并发性心理症状的临床治疗策略提供参考.
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