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Updated: Jun 30, 2025

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RNA结合蛋白可能会调节膝关节骨关节炎进展过程中异位性基因的替代拼接

Zheng Zhang1, Limei Dong2, Hai Tao3

  • 1Department of Orthopedics, Renmin Hospital of Wuhan University, 238, Jiefang Road, Wuchang District, 430060, Wuhan, Hubei, China. zhangzheng_fr@126.com.

BMC genomics
|March 20, 2024
PubMed
概括

研究了膝关节骨关节炎 (OA) 中的替代拼接 (AS) 失调. 像CUL4B这样的RNA结合蛋白可能会控制亡基因AS,识别XAF1作为OA的潜在生物标志物.

关键词:
另一个替代拼接.细胞灭亡 (apoptosis) 是一种死亡的过程.共同变异 共同变异 共同变异不同表达的基因.膝关节骨关节炎是一种关节炎.这是一种RNA结合蛋白.转录组 转录组就是一个转录组.

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