伊朗婴儿的爆发性冠状病毒病2019年脑膜炎:一个病例系列
Shahla Afsharpayman1, Sedigheh Madani2,3, Susan Amirsalari1
1Department of Pediatrics, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, I. R. of Iran.
Journal of medical case reports
|March 20, 2024
概括
Fulminant脑膜炎可能是2019年新冠肺炎的首要症状在婴儿中,即使没有其他器官参与. 早期考虑COVID-19对于诊断严重疾病儿童脑膜炎至关重要.
科学领域:
- 儿科神经学 儿科神经学
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 通常表现为儿童的呼吸道和胃肠道症状.
- 这份报告强调了三名患有严重脑膜炎的婴儿作为COVID-19的主要症状.
研究的目的:
- 报告三个由COVID-19引起的 fulminant脑膜炎的儿科病例.
- 强调在出现严重脑膜炎症状的婴儿中考虑COVID-19的重要性.
主要方法:
- 一系列病例描述了三名患有严重脑膜炎的婴儿.
- 脑脊液 (CSF) 分析,包括PCR和培养常见病原体.
- 在CSF和血液样本上进行COVID-19 PCR测试.
主要成果:
- 这三名婴儿都患有严重的脑膜炎,其特征是脑脊髓液中控制不良的和红细胞 (RBC).
- 首次对细菌病原体的CSF分析是负的.
- 在CSF中,COVID-19 PCR呈阳性,证实SARS-CoV-2感染是脑膜炎的原因.
结论:
- 应怀疑COVID-19脑膜炎在患有和CSF异常的重症婴儿中.
- 治疗考虑因素可能包括皮质类固醇,雷梅西维尔和静脉注射免疫球蛋白 (IVIG).
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