饮食中的蛋白质水平对幼生猪肠道功能和炎症的影响
Sarah C Pearce1, Mitchell J Nisley2, Brian J Kerr1
1USDA-ARS National Laboratory for Agriculture and the Environment, Ames, IA, USA.
Journal of animal science
|March 20, 2024
概括
与普遍认为的相反,高原蛋白 (CP) 饮食并没有对幼猪肠道健康产生负面影响. 然而,高CP的饮食确实改变了叶屏障功能和营养物质的运输,这表明对肠道功能的区域影响.
科学领域:
- 动物科学动物科学
- 营养科学 营养科学
- 胃肠病学 胃肠病学
背景情况:
- 哺乳期后养的高原蛋白 (CP) 饮食 (21-26%) 经常被避免,因为人们担心腹和病原体负担增加.
- 这些担忧表明对小猪健康和生长表现的负面影响.
研究的目的:
- 调查低与高的饮食CP对新断奶猪肠道功能的影响.
- 分析关键参数,包括肠道屏障完整性,营养物质运输,炎症和便干燥物质.
主要方法:
- 120头猪在两个阶段被养21天的低CP (17%) 或高CP (24%) 饮食.
- 评估了肠道屏障的完整性 (大肠和结肠),营养物质的运输 (葡萄糖,谷氨酸) 和炎症 (细胞因子).
- 还监测了便干物 (DM) 和生长表现.
主要成果:
- 在饮食治疗之间没有观察到生长速度,料摄入量,便一致性或结肠屏障功能的差异.
- 在养高CP饮食的猪中发现了更高水平的INTERLEUKIN-8 (IL-8) 和IL-18.
- 在高CP养的猪中,叶屏障功能表现出改善的趋势,而葡萄糖和谷氨酸运输减少.
结论:
- 低CP饮食似乎不会损害结肠屏障功能,便DM或断奶猪的炎症.
- 饮食中的CP水平可以在区域范围内影响肠道功能,特别是改变乳腺屏障完整性和营养物质的运输.
- 需要进一步的研究,以了解这些区域变化对猪整体健康和表现的影响.
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