在2型糖尿病中通过温度值测试评估神经病变
Archana Gaur1, Sakthivadivel Varatharajan2, Roja Katta3
1Department of Physiology, All India Institute of Medical Sciences, Hyderabad, Telangana, India.
International journal of applied & basic medical research
|March 20, 2024
概括
温度值测试有效地诊断出早期糖尿病小纤维神经病变. 年龄和糖尿病持续时间是关键的危险因素,下肢热值测试显示高灵敏度.
科学领域:
- 神经学 神经学
- 内分泌学 在内分泌学.
- 糖尿病学 糖尿病学
背景情况:
- 糖尿病神经病变的诊断是具有挑战性的,因为无症状的呈现.
- 定量感官测试,神经传导研究和自主测试是标准的诊断工具.
- 温度值测试 (TTT) 显示了早期小纤维神经病变检测的前景.
研究的目的:
- 为了评估2型糖尿病患者的小纤维神经病变,使用TTT.
- 为了将TTT发现与年龄,糖尿病持续时间和脂质概况相关联.
- 评估TTT在早期糖尿病神经病变诊断中的有效性.
主要方法:
- 100名2型DM患者 (40-65岁) 在伦理学批准后被录取.
- 神经病的评估包括密歇根神经病查仪器 (MNSI) 和TTT.
- 收集了血糖状况,脂质状况和体检数据.
主要成果:
- 通过TTT的小纤维神经病变的患病率为63%.
- 神经病症组的MNSI B分数显著提高,热/冷值发生变化.
- 年龄和糖尿病持续时间与神经病变有正相关;下肢热门值显示出强烈的正相关性.
结论:
- 年龄和糖尿病持续时间是糖尿病外围神经病变的独立风险因素.
- 小纤维神经病变之前的运动神经病变的发展.
- 下肢热值测试是诊断小纤维神经病变的敏感方法.
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