应该更多地关注与Omicron相关的败血症:中国南部的一项多中心回顾性研究
Ling Sang1,2,3, Yonghao Xu1,2, Yongbo Huang1,2
1State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Journal of thoracic disease
|March 20, 2024
概括
奥米克朗变种感染可以导致住院患者的败血症,增加重症监护室转移和死亡的风险. 早期SOFA评分评估对于识别2019年冠状病毒病患者的败血症至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
背景情况:
- 尽管SARS-CoV-2的Omicron变种具有很高的传染性,但其对败血症发病率和结果的影响尚不清楚.
- 了解与Omicron相关的败血症对于管理住院患者至关重要.
- 这项研究调查了住院患者的Omicron相关性败血症.
研究的目的:
- 为了确定与Omicron相关的败血症的发生率,使用败血症3.0定义.
- 探索与Omicron相关的败血症和临床特征之间的关系.
- 评估与Omicron相关的败血症的预后影响.
主要方法:
- 一项针对住院患有SARS-CoV-2感染 (Omicron变种) 的成年人的多中心回顾性研究.
- 在入院时使用顺序器官衰竭评估 (SOFA) 得分来识别败血症.
- 结果包括ICU转移和死亡率;分析了SOFA分数组件.
主要成果:
- 299名患者中有147名 (64.19%) 在入院时患有败血症.
- 败血症患者的SOFA分数显著更高,预后更差,包括增加ICU转移和死亡率.
- 严重病例和伴随性疾病,如糖尿病和心血管疾病在败血症组中更为普遍.
结论:
- 在感染Omicron的患者中,显著比例的患者在入院时出现了败血症.
- 与Omicron相关的败血症与预后较差和死亡率增加有关.
- 早期SOFA评分评估对于在住院COVID-19患者中识别病毒性败血症至关重要.
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