长期肺癌幸存者的特征和患者报告的结果
Ana Fonseca1, Mariana Antunes2, João Firmino-Machado3,4
1Multidisciplinary Thoracic Tumours Unit, Pulmonology Department, Centro Hospitalar Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.
Journal of thoracic disease
|March 20, 2024
概括
长期肺癌幸存者 (LTLCS) 的数量正在增长,但许多人面临着影响其生活质量的重大挑战. 持续的,以患者为中心的护理对于管理他们持续的健康需求至关重要.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 患者报告的结果
背景情况:
- 肺癌查和治疗的进步导致了长期肺癌幸存者 (LTLCS) 人口的增加.
- 对了解LTLCS的特征和结果的兴趣正在增长.
- 本研究解决了评估LTLCS流行,人口统计和患者报告结果 (PRO) 的需要.
研究的目的:
- 为了确定LTLCS的流行率.
- 为了描述LTLCS的患者群体.
- 评估生活质量 (QoL) 和LTLCS患者报告的结果.
主要方法:
- 进行了一项横截面研究,涉及2012年1月至2016年12月期间被诊断患有原发性肺癌的患者,总生存期 (OS) 超过5年.
- 使用了自我管理的问卷,包括欧洲癌症研究和治疗组织的生命质量问卷核心-30 (EORTC QLQ-C30) 和患者健康问卷-4 (PHQ-4).
- 开放式问题探讨了QoL和改进建议,并分析了与QoL相关的因素.
主要成果:
- 767名患者中有158名 (20.6%) 被确定为LTLCS患者,其比例每年都在增加.
- LTLCS主要是男性 (70.9%),平均年龄为65岁. 大多数人患有腺癌 (57%),诊断在早期 (66.2%),虽然8.9%的诊断在第四阶段.
- 通过PHQ-4在36%的LTLCS中确定了精神困扰;较低的QoL与更高的焦虑率 (35.3%) 和抑郁率 (27.9%) 相相关. 疼痛和疲劳是最具影响力的症状,患者希望得到更好的医疗保健和社会支持.
结论:
- LTLCS的患病率正在增加,突出显示越来越多的人群需要特殊的护理考虑.
- LTLCS经历了相当大的疾病负担,高焦虑和抑郁率会对他们的生活质量产生负面影响.
- 多学科,以患者为中心,持续的随访护理对于管理LTLCS复杂需求至关重要.
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