语音错误的时间和位置是由直接皮质刺激引起的
Heather Kabakoff1, Leyao Yu2, Daniel Friedman1
1Department of Neurology, New York University School of Medicine, New York, NY 10016, USA.
Brain communications
|March 20, 2024
概括
绘制语音停止延迟的地图揭示了语音生产中的不同功能角色. 在部和部区域的较短延迟表明运动执行,而在前部区域的较长延迟表明语音规划.
科学领域:
- 神经科学是一个神经科学.
- 神经外科 神经外科
- 语音制作 语音制作
背景情况:
- 直接电皮刺激是神经外科手术期间绘制雄辩的皮层区域的黄金标准.
- 然而,这种方法缺乏关于受影响的潜在认知过程的特异性.
- 了解语音停止的时间动态可以区分区域特定的功能.
研究的目的:
- 为了绘制语音停顿的时间动态图,跨越西尔维亚大皮层.
- 量化刺激和语音缺陷之间的延迟,以区分认知过程.
- 为了证实关于语言生产中不同区域特定的功能角色的假设.
主要方法:
- 对20名患者进行了回顾性观察性研究,这些患者接受了内EEG监测.
- 在临床床床边语言映射期间自动语音任务.
- 从刺激开始到语音停止开始计算的语音停止的延迟,控制个人语音速度.
主要成果:
- 基于运动的语音停顿主要发生在感觉运动皮质中,具有中等延迟 (峰值为0.47秒).
- 较短的延迟时间被观察到在上边缘环 (0.46s),上环 (0.51s) 和中环 (0.54s) 中,这表明运动执行干扰.
- 较长的延迟时间在下额头回环 (0.95秒) 和腹部感觉运动皮质中表明干扰了更高层次的语音规划.
结论:
- 语音停止延迟预测了皮层刺激中断的潜在认知过程.
- 状垂体区域 (超边缘和上状垂体) 参与发言的运动执行.
- 下额和腹部感觉运动皮质参与了语言生产的规划阶段.
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