相关实验视频

Updated: Jun 30, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

在SLE患者的心脏MRI上减少左心室功能与SLE疾病活动和炎症的测量相关

Audrey M Hagiwara¹, Erica Montano¹, Gantseg Tumurkhuu¹

¹Division of Rheumatology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA.

Journal of radiology and clinical imaging

|March 20, 2024

概括

40%的患有系统性红斑狼 (SLE) 的女性表现出冠状动脉微血管功能障碍 (CMD). 心脏MRI显示SLE患者心脏功能受损和与疾病活动相关的扩散性纤维化.

科学领域:

心脏病学心脏病学
类风湿病学类风湿病学
医疗成像医学成像

背景情况:

患有系统性红斑狼 (SLE) 的女性面临心血管疾病 (CVD) 的风险增加.
胸痛在SLE患者中很常见,通常没有阻塞性冠状动脉疾病 (CAD).
心声图显示左心室 (LV) 功能减少,与SLE活动相关.

研究的目的:

通过使用心脏MRI (cMRI) 对女性SLE患者的SLE,炎症生物标志物和心脏功能之间的关系进行调查.
评估SLE患者的心脏结构,功能和组织特征,有或没有胸痛.

主要方法:

应激休息的cMRI用于评估LV结构,功能,组织特征和心肌输液储备指数 (MPRI).
冠状动脉微血管功能障碍 (CMD) 被定义为MPRI <1.84.4.
分析了血清炎症标志物,并评估了临床和cMRI数据之间的关系.

主要成果:

40%的SLE受试者表现出CMD (MPRI<1.84). 在SLE受试者中,有40%的SLE受试者表现出CMD (MPRI<1.84).
与对照组相比,SLE受试者具有较高的LV体积/质量和较低的LV缩功能.
SLE损伤指数 (SLICC DI) 与更差的心脏功能和更高的T1值相关;CRP与更高的心脏输出相关.

结论:

40%的女性SLE队列呈现CMD.
SLICC DI与心脏功能受损和扩散性纤维化相关,这表明疾病活动和心脏重塑之间存在联系.
非侵入性cMRI显示出对SLE患者心血管健康的监测有希望.

关键词:

冠状动脉微血管功能障碍冠状动脉微血管功能障碍心肌输血储备指数 - 心肌输血储备指数系统性狼红斑性狼

更多相关视频

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

Published on: June 20, 2014

Histological Quantification of Chronic Myocardial Infarct in Rats

Histological Quantification of Chronic Myocardial Infarct in Rats

Published on: December 11, 2016

相关概念视频

Imaging Studies for Cardiovascular System III: X-Ray

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...