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Updated: Jun 30, 2025

A Novel Method: Super-selective Adrenal Venous Sampling
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在产生阿尔多素的腺瘤中CTNNB1和GNA11的双体突变

Kazutaka Nanba1,2,3, Amy R Blinder3, Aaron M Udager4,5,6

  • 1Department of Endocrinology and Metabolism, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.

Frontiers in endocrinology
|March 20, 2024
PubMed
概括

在CTNNB1和GNA11基因的双重突变被发现在罕见的阿尔多斯特产生腺瘤 (APA). 这些APAs表现出正常的球状区域的特征,并且可以在没有特定生殖关联的成年人中发生.

关键词:
在 CTNNB1 找在CYP11B2中.在 GNA1111 中使用.产生阿尔多斯特的腺瘤主要的阿尔多斯顿主义.身体突变是一种体质突变.

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