皮肤而不是背部根刺激可以减少胸部运动中脊髓损伤的高:单一病例报告
Brandon Lieu1, Dirk G Everaert1, Chester Ho1,2
1Division of Physical Medicine and Rehabilitation, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Journal of neurophysiology
|March 20, 2024
概括
在脊髓损伤 (SCI) 患者中,通过皮肤进行电刺激 (TES) 应用到下背部,减少腿部超. 这种非侵入性方法在刺激过程中对过度肌肉度提供按需的缓解.
科学领域:
- 神经科学是一个神经科学.
- 康复医学 康复医学 康复医学
- 生物医学工程 生物医学工程
背景情况:
- 过度肌肉度 (高肌度) 是脊髓损伤 (SCI) 患者的常见和使人虚弱的挑战.
- 目前用于SCI相关的高血压的治疗方法缺乏按需和局部应用,需要新的治疗方法.
研究的目的:
- 为了研究通过皮肤电刺激 (TES) 应用到下背部的疗效,减少腿部高血压在一个患者的运动完全胸部SCI.
- 探索TES引起的双边减少腿部肌肉的潜在机制.
主要方法:
- 一个商业TES设备被应用在50或150赫兹的下背部 (中线和横部放置) 的参与者与机器完全SCI.
- 使用摆摆测试测量了腿部高度,并评估了脊柱反射 (H反射和皮肌反射).
- 刺激参数包括在脊柱上放置阴极 (T11-L2) 和阳极 (L3-L5).
主要成果:
- 对胸前腹部区域应用的TES在刺激过程中导致腿部超完全消失.
- 在释放后,下腿下落距离的显著增加量化了音调的减少.
- TES调节脊柱反射,增加H反射和改变皮肤肌肉反射模式.
结论:
- 胸腔带TES证明了作为一种非侵入性方法来降低慢性,运动完整的SCI的腿部超的潜力.
- 该机制可能涉及皮肤和肌肉关节的激活,从而通过内部神经元通路对运动神经元活动进行双边抑制.
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