通过组织居民1型先天性淋巴细胞和杀手性先天性类似T细胞的癌症免疫力

Jing Zhang1, Albert M Li1, Emily R Kansler1

  • 1Immunology Program, Memorial Sloan Kettering Cancer Center, New York City, New York, USA.

Immunological reviews
|March 20, 2024
PubMed
概括

癌症免疫监测涉及从先天性淋巴细胞 (ILCs) 和先天性类似T细胞 (ILTCKs) 预先连接的免疫力,补充自适应性T细胞反应. 针对这些细胞提供了新的癌症免疫疗法途径.

相关概念视频

Cells of the Innate Immune Response01:28

Cells of the Innate Immune Response

The innate immune response is an immediate and non-specific response against pathogens, acting swiftly to prevent the spread of infections. The primary cells involved in this response are phagocytes and natural killer (NK) cells.
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
1.6K
Cytotoxic T Cells-mediated Immune Response01:27

Cytotoxic T Cells-mediated Immune Response

Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
907
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
68.2K
Immune Surveillance by NK Cells and Phagocytes01:25

Immune Surveillance by NK Cells and Phagocytes

Immune surveillance is an integral part of the innate immune system, involving the continuous monitoring of peripheral tissues to detect and respond to pathogens, infected cells, or cancerous cells. This surveillance is conducted primarily by natural killer (NK) cells and phagocytes, which employ distinct but complementary mechanisms to identify and eliminate threats.
Natural Killer Cells: The Fast Responders
NK cells are large granular lymphocytes found in the blood and lymphatic system. These...
1.4K