运动性发作为2级质瘤患者提供整体生存益处
Sam Fairclough1,2, Paul Chumas3, John Goodden3
1Adult Neurology, Leeds Teaching Hospitals, Leeds, UK.
Epilepsia
|March 20, 2024
概括
常见于世界卫生组织 (WHO) 2级质瘤患者,运动发作与改善生存率有关. 这表明,发作类型会影响质瘤患者的预后.
科学领域:
- 神经瘤学神经瘤学
- 发病学 (Epileptology) 是一个专业的学科.
- 神经外科 神经外科
背景情况:
- 是世界卫生组织 (WHO) 2级质瘤的常见并发症,通常作为最初的症状呈现.
- 了解这种患者群体的流行病学对于管理他们的护理至关重要.
研究的目的:
- 调查世卫组织2级质瘤患者的患病率和特征.
- 确定发作类型对这一群体的整体存活率的影响.
主要方法:
- 对228名患有世卫组织2级质瘤的患者 (1997-2021) 电子健康记录的回顾性审查.
- 数据收集包括人口统计,发病率和发作半学.
- 考克斯比例危险模型用于分析发作类型对生存率的影响.
主要成果:
- 在86.4%的患者中诊断出.
- 男性患者患的患病率更高,并且更有可能经历焦点到双边强力克隆性发作.
- 左侧瘤与增加的焦点到双边性-克隆性发作的发生有关.
- 运动发作活动与10年死亡风险降低65%相关,独立于其他预后因素.
结论:
- 运动活动是世卫组织2级质瘤的常见特征,与生存益处有关.
- 主导半球中的瘤可能更容易发展双边增强性-克隆性活性.
相关概念视频
Treatment Resistant Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Treatment Resistent Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Seizures: Classification
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:


