在英国口腔健康和玻璃眼特征之间的关系
Rachel H Lee1, Jae H Kang2, Janey L Wiggs3
1New York Eye and Ear Infirmary of Mount Sinai.
Journal of glaucoma
|March 20, 2024
概括
这项研究发现,口腔健康不良与玻璃眼或高眼内压 (IOP) 之间没有联系. 需要进一步的研究来证实这种对临床诊断的口腔健康状况的无关联.
科学领域:
- 眼科医生 眼科 眼科
- 牙科医学 牙科医学
- 公共卫生 公共卫生
背景情况:
- 糟糕的口腔健康与全身炎症有关,可能影响神经退行性疾病.
- 口腔健康状况与眼之间的关系是不可逆转失明的主要原因,需要进一步调查.
研究的目的:
- 调查自我报告的口腔健康状况与玻璃眼的流行率之间的联系.
- 检查口腔健康和眼内压力 (IOP),黄斑视网膜神经纤维层 (mRNFL) 厚度和状细胞内状层 (mGCIPL) 厚度之间的关系.
主要方法:
- 对英国生物库参与者的横截面分析 (n=170,815).
- 自我报告的口腔健康状况被分类.
- 多变量回归模型被用于评估与眼,IOP,mRNFL和mGCIPL的关联,并对潜在的混因素进行调整.
主要成果:
- 没有发现自我报告的口腔健康状况与玻璃眼患病率 (OR:1.04,95% CI:0.95-1.14) 之间有显著的关联.
- 在患有口腔疾病的个体中,眼内压力 (IOP) 略低一些,特别是那些牙松动或戴假牙的人.
- 斑点视网膜神经纤维层 (mRNFL) 的测量在口腔健康状况较低的人中较低,但状细胞内层 (mGCIPL) 的测量显示没有显著差异.
结论:
- 自我报告的口腔健康状况与玻璃眼瘤或眼内压升高的风险增加无关.
- 这些发现表明,口腔健康和玻璃眼之间没有任何关联,因此需要对临床诊断的疾病进行进一步调查.
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