体重是否会影响住院婴儿RSV支气管炎的过程?
Shelly Tamir1, Inbal Golan-Tripto1,2,3, Itai Hazan1,4
1Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
European journal of pediatrics
|March 20, 2024
概括
患有呼吸道综合体病毒 (RSV) 支气管炎的低体重婴儿面临更高的严重后果风险,包括儿科重症监护室 (PICU) 的入院和长时间住院. 超重的婴儿没有显示严重程度的增加.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 急性支气管炎是全球婴儿住院的主要原因.
- 婴儿体重对呼吸道综合体病毒 (RSV) 支气管炎严重性的影响尚不清楚.
- 异常体重状况与传染病发病率和死亡率的增加有关.
研究的目的:
- 调查婴儿体重状况与RSV支气管炎的严重程度之间的联系.
- 为了确定患有RSV支气管炎的住院婴儿体重不足和超重的特定风险.
主要方法:
- 对1936名因RSV支气管炎住院治疗的24个月以下婴儿进行了回顾性队列研究 (2018-2022).
- 婴儿根据体重被分为体重不足 (<5百分比),体重正常和超重 (>85百分比) 的婴儿.
- 分析了儿科重症监护室 (PICU) 的入院率,入院时间 (LOS) 和低血率.
主要成果:
- 与体重正常的婴儿相比,体重不足的婴儿显示出显著更高的PICU入院率 (9.1%与3.5%) 和延长的LOS (3.13与2.79天).
- 低血症在体重不足的婴儿中更频繁 (23%对15%).
- 多变量分析证实,体重不足的婴儿患PICU入院风险增加了2.01倍,长期LOS风险增加了1.42倍. 超重状态与严重程度的增加没有关联.
结论:
- 患有RSV支气管炎住院的体重不足的婴儿经历了更严重的疾病过程和更高的并发症率.
- 这个小组需要仔细关注和监测,因为他们增加了PICU入院和长时间住院的风险.
- 体重状况是影响婴儿RSV支气管炎严重程度的独立因素.
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