系统性右心室的心肌工作及其与结果的关联
Elena Surkova1, Bálint Károly Lakatos2, Alexandra Fábián2
1Royal Brompton and Harefield Hospitals, Part of Guy's and St Thomas' NHS Foundation Trust, Sydney Street, Chelsea, London, SW3 6NP, UK. elena.surkova.md@gmail.com.
The international journal of cardiovascular imaging
|March 20, 2024
概括
心肌工作参数,包括全球建设性工作 (GCW) 和全球工作指数 (GWI),可靠地评估系统右心室 (SRV) 缩功能. 这些新的心声回声测量与SRV喷射率相关,并预测SRV患者的死亡率.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏机械学 心脏机械学
背景情况:
- 系统右心室 (SRV) 在评估缩功能方面提出了独特的挑战.
- 传统的心声回声学参数可能无法完全捕捉SRV的机械性能.
- 心肌工作指数为量化心脏工作负载提供了一种新的方法.
研究的目的:
- 评估SRV患者心肌功能参数的临床和预后意义.
- 为了将心肌工作指数与SRV功能的已建立的心声学测量结果相关联.
- 评估心肌功能与临床结果的关联,包括死亡率和心脏移植.
主要方法:
- 38名SRV患者的心声学评估,包括3D心声学衍生的喷射分数 (EF),2D纵向应变和心肌工作分析 (全球建设性工作 - GCW,全球工作指数 - GWI).
- 心肌工作参数与SRV EF,BNP水平和三回严重程度之间的相关性分析.
- 使用考克斯回归的生存分析,以确定所有原因死亡率和心脏移植的综合终点肌肉心脏工作参数的预后值.
主要成果:
- 全球建设性工作 (GCW) 和全球工作指数 (GWI) 与3DE衍生的SRV射出分数 (EF) 显示了中度的相关性.
- GCW和GWI与BNP水平呈现出强烈的逆相关性,表明SRV功能较差.
- 患有中度/严重三腹吐的患者表现出明显较低的GCW和GWI.
- 较低的GCW和GWI显著与所有原因死亡率和心脏移植风险的增加有关.
- 考克斯回归分析确定GCW,GWI和3DESRV参数是不利结果的最佳预测指标,表现优于纵向菌株.
结论:
- 新的回声心脏学心肌工作参数,GCW和GWI,可提供SRV缩功能的可靠量化.
- 这些参数与SRV EF,BNP水平和三腹的严重程度密切相关.
- GCW和GWI是SRV患者全因死亡率和心脏移植的重要独立预测因素,提供了有价值的预后信息.
关键词:
遗传性心脏病是一种先天性心脏病.心肌功能的工作.斑点追踪应变回声心脏图谱 (speckle-tracking strain echocardiography) 是一种可以追踪斑点的应变回声心脏图谱.系统性右心室系统性右心室三维心声回声图是指三维心声回声图.更多相关视频
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