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胃肠组织等离子体与小肠穿孔:20年的经验
Jack W Sample1, Jennifer A Yonkus2, Maxwell D Mirande2
1Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. sample.jack@mayo.edu.
Updates in surgery
|March 20, 2024
概括
小肠穿孔是胃肠组织等离子体病的罕见并发症,特别是在免疫功能低下的患者中. 手术切除和抗真菌疗法为这种严重疾病提供了成功的治疗结果.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 手术病理学手术病理学
背景情况:
- 胃肠道的干扰在散布性基因质等离子体中很常见,影响到70%的患者.
- 小肠穿孔是一种极其罕见的胃肠组织等离子体病的表现.
研究的目的:
- 描述小肠穿孔的临床表现,管理和结果在患有胃肠组织等离子体的患者.
- 强调在免疫受损个体中对胃肠道穿孔的差异诊断中考虑基因质等离子体的重要性.
主要方法:
- 从2002年到2022年对单一机构案件系列的回顾性审查.
- 纳入标准:年龄≥18岁的患者因胃肠组织等离子体引起的小肠穿孔而接受治疗.
- 收集的数据:人口统计,并发病,治疗和结果.
主要成果:
- 确定了五名患者 (平均年龄54岁),他们患有诸如克罗恩病和固体器官移植等潜在疾病.
- 所有患者都服用慢性免疫抑制药物,包括TNF-α抑制剂和皮质类固醇.
- 所有患者都接受了小肠切除,并接受了抗真菌疗法 (安福特乙,然后是口服抗真菌药物),没有出现手术并发症.
结论:
- 在接受免疫抑制治疗的患者中,在胃肠道穿孔的差异诊断中应考虑血清性质,特别是在特有病区.
- 由于胃肠组织等离子体的小肠穿孔可以通过手术切除和抗真菌治疗来治疗.
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