通过整合蛋白质语言模型来预测单个序列蛋白质结构

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Updated: Jun 30, 2025

A Protocol for Computer-Based Protein Structure and Function Prediction
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A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

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Xiaoyang Jing1, Fandi Wu1,2, Xiao Luo3,4

  • 1MoleculeMind Ltd., Beijing 100084, China.

Proceedings of the National Academy of Sciences of the United States of America
|March 20, 2024
PubMed
概括

一种名为RaptorX-Single的新方法仅使用单个序列来预测蛋白质结构,其性能优于对抗体和具有有限同类蛋白质的现有工具. 这种深度学习方法可以在没有多个序列对齐的情况下推进蛋白质结构预测.

关键词:
抗体结构预测 抗体结构预测蛋白质语言模型蛋白质结构预测 蛋白质结构预测单个突变效应的单一突变效应.单个序列蛋白质结构的修订

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