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Updated: Jun 30, 2025

Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses
12:20

Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses

Published on: December 29, 2015

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最小的细菌细胞JCVI-syn3B作为一个底盘来研究细菌和哺乳动物细胞之间的相互作用

Daniela Matias de C Bittencourt1,2, David M Brown3, Nacyra Assad-Garcia3

  • 1The J. Craig Venter Institute, 4120 Capricorn Lane, La Jolla, California 92037, United States.

ACS synthetic biology
|March 20, 2024
PubMed
概括

研究人员开发了一种合成的Mycoplasma mycoides (Mmc) 系统,以识别介导宿主细胞相互作用的基因. 一种缩小基因组菌株 (JCVI-syn3B) 成功识别了8个基因,这些基因对人类细胞的Mmc附着和细胞形成至关重要.

关键词:
细菌-哺乳动物细胞相互作用细胞培养培养的细胞培养.免疫反应的免疫反应.最少的细胞是最小的细胞.菌质体中的菌质体.

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