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Updated: Jun 30, 2025

An Optimized Quantitative Pull-Down Analysis of RNA-Binding Proteins Using Short Biotinylated RNA
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对比性预训练和3D卷积神经网络用于RNA和小分子结合亲和力预测

Saisai Sun1, Lin Gao1

  • 1School of Computer Science and Technology, Xidian University, No.266 Xinglong Section of Xi Feng Road, Xi'an, Shaanxi, 710126, China.

Bioinformatics (Oxford, England)
|March 20, 2024
PubMed
概括

预测RNA-小分子结合亲和力对于药物发现至关重要. 新的深度学习模型RLaffinity使用3D结构准确预测这种亲和力,优于现有的方法.

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