通过计算方法从天然产品数据库中发现潜在的WRN抑制剂

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Tao Jiang1, Yunfeng Zhang1, Shuihong Yu2

  • 1Navy Anqing Hospital, Anqing, China.

Journal of molecular graphics & modelling
|March 20, 2024
PubMed
概括

研究人员确定了天然化合物作为维纳综合征 (WRN) 蛋白的潜在抑制剂,这是微卫星不稳定性 (MSI) 癌症的点,如结肠直肠癌. 这项计算研究为开发新的MSI癌症疗法提供了基础.

关键词:
动力学模拟的动力学模拟.分子对接是分子对接.自然产品是自然产品.一个TI模拟的TI模拟.作为WRN抑制剂的使用.

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