在患有帕金森病和运动细分的人群中,快速抓握的性能受损
Rebecca J Daniels1, David Grenet2, Christopher A Knight3
1Department of Kinesiology and Applied Physiology, University of Delaware, 211AC The Tower at STAR, 100 Discovery Blvd, Newark, DE, USA.
Human movement science
|March 20, 2024
概括
与健康的成年人相比,患有帕金森病 (PD) 的人在手握任务时表现出较慢的力变化. 运动细分,以异常的力量模式为特征,在一些PD患者中存在,并与肌肉活动中断有关.
科学领域:
- 神经机械学 神经机械学
- 发动机控制器的控制器
- 神经退行性疾病 神经退行性疾病
背景情况:
- 布拉迪基尼西亚 (缓慢运动) 是帕金森病 (PD) 的一个关键症状.
- 导致PD缓慢的潜在神经机械缺陷尚未完全理解.
- 之前的研究表明,由于电肌图 (EMG) 静止期,单关节运动中的运动细分.
研究的目的:
- 为了比较PD患者和健康对照者 (年轻人和老年人) 之间的手握力变化.
- 调查PD患者手握力和EMG措施中运动细分的存在.
主要方法:
- 参与者在不同的力量水平下进行了快速的等比手握收缩.
- 电肌图 (EMG) 被记录在握力曲器和伸缩器上.
- 关键指标包括力量发展/放松率,力时间曲线细分和EMG爆发分析.
主要成果:
- 与健康成年人相比,患有PD的人表现出较慢的力变化 (持续时间较长,速度较低).
- 在22名患有PD的6名患者中,确定了运动细分.
- 患有PD的个体表现出更多的EMG爆发,这与力段数量相关.
结论:
- 在帕金森病中,同度握手任务适合研究快速运动控制.
- 患有PD的人在手持任务中表现出受损的速度控制.
- 运动细分是PD患者手握中可检测的现象,与神经肌肉控制改变有关.
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