创伤后应激障碍,抑郁症和治疗结果:在住宿创伤后应激障碍计划的现役人员中进行了潜在的个人资料分析
Alexander C Kline1, Nicholas Otis1, Kaitlyn E Panza2
1Psychological Health and Readiness, Naval Health Research Center, San Diego, CA, USA; Leidos, Inc., San Diego, CA, USA.
Journal of psychiatric research
|March 20, 2024
概括
这项研究在男性军人中确定了四个不同的抑郁症和创伤后应激障碍 (PTSD) 同时发生的子组. 在这些PTSD和抑郁症症状概况中,治疗结果有显著的差异.
科学领域:
- 心理健康 心理健康
- 精神病学是一个精神病学.
- 军事心理学 军事心理学
背景情况:
- 抑郁症和创伤后应激障碍 (PTSD) 经常在现役服役人员中同时发生.
- 这种并发性疾病的症状异质性及其对治疗结果的影响,特别是在住宅环境中,仍然不明确.
研究的目的:
- 在接受住院治疗的男性军人中确定伴随性PTSD和抑郁症的基于症状的子组.
- 检查这些已识别的子组对10周的住宿PTSD治疗计划的反应.
主要方法:
- 隐性概况分析 (LPA) 用于根据PTSD和抑郁症症状概况对282名男性服务人员进行分类.
- 在治疗前和后以及治疗期间每周使用PTSD检查清单-军事版本和患者健康问卷-8收集症状数据.
- 用多级模型来比较每个已识别的子组在治疗过程中的症状变化.
主要成果:
- 四个不同的子组出现了:抑郁型,避开型,中度型和焦虑型.
- 在四个子组中观察到PTSD和抑郁症症状治疗反应的显著差异.
- 适度子组显示PTSD症状改善较少,而痛苦和抑郁子组经历了最大的抑郁症状减少.
结论:
- 这项研究提供了一种初步模型,以了解服务人员在伴随性PTSD和抑郁症中的症状异质性.
- 不同的症状形状与住院PTSD治疗的不同反应有关,突出显示了针对性干预的必要性.
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