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卡塞普辛B:瘤治疗的黎明

Fuxian Liu¹, Ting Zhou², Shangzu Zhang¹

¹Provincial-Level Key Laboratory for Molecular Medicine of Major Diseases and the Prevention and Treatment with Traditional Chinese Medicine Research in Gansu Colleges and Universities, Gansu University of Chinese Medicine, Lanzhou, China.

European journal of medicinal chemistry

|March 20, 2024

概括

甲素B (CTSB) 是癌症发展中的重要蛋白酶. 这篇评论探讨了CTSB的情况.

科学领域:

分子生物学分子生物学
在瘤学瘤学.
生物化学生物化学

背景情况:

甲素B (CTSB) 是一种溶酶蛋白酶,涉及到各种细胞过程.
对CTSB的失调越来越被认为是癌症发病的一个重要因素.

研究的目的:

阐明CTSB在癌症进展中的多方面的作用,包括瘤生长,迁移,入侵和转移.
审查目前针对癌症治疗中CTSB的治疗策略.
探索传统中医药在调节癌症治疗中CTSB表达的潜力.

主要方法:

文献综述和对CTSB现有研究的综合.
分析CTSB对癌症的结构和功能贡献.
对针对CTSB的药物进行的临床前和临床研究的审查.
对传统中医药对CTSB的影响研究的评估.

主要成果:

通过参与瘤生长,血管新生,侵袭,转移和自的过程,CTSB促进癌症的发展.
针对CTSB的几种药物正在接受癌症治疗的调查.
传统中国医学通过调节CTSB表达提供了潜在的治疗途径.

结论:

CTSB是癌症治疗的关键分子标.
准CTSB为开发新型抗癌药物提供了一个有前途的战略.
传统中医药通过调节CTSB.具有创新癌症治疗的潜力.

关键词:

自自是一种自的过程.在CTSB中,CTSB是CTSB.癌症癌症癌症癌症传统的中国医学是传统的中国医学.瘤是一个瘤.

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