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Christo J Botha¹, Magdaleen Vosser², Mohammed I A Ibrahim¹

¹Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.

Toxicon : official journal of the International Society on Toxinology

|March 20, 2024

概括

在南非,牛在牧场上放牧后,出现了红黑色素质,因为这些牧场中含有印地戈. 这种植物含有印加素,它可能会导致牛的脏损伤和深色尿液.

科学领域:

兽医毒理学兽医毒理学
动物病理学动物病理学
植物与动物之间的相互作用

背景情况:

牛的色素是一种影响动物健康的令人担忧的情况.
众所周知,白种在牲畜中引起毒性.
之前的报道记录了巴西的Indigofera suffruticosa诱导的血红素.

研究的目的:

为了调查南非放牧牛中红黑色素质的原因.
为了确定导致观察到的临床症状的有毒植物.
阐明色素的机制和潜在的毒性.

主要方法:

对受影响的牛群进行现场调查.
临床和验尸检查. 临床和验尸检查.
尿液分析和脏的组织病理学检查.
使用UPLC-UV-qTOF/MS.进行植物材料 (Indigofera cryptantha) 和尿液的化学分析.

主要成果:

确定了两例牛表现出红黑色素质的病例.
发现Indigofera cryptantha在受影响的牧场上被大量放牧.
在I.cryptantha中检测到Indican (氧β-葡萄糖化物),在受影响牛的尿液中检测到氧硫酸.
组织病理学发现管损伤,一个公牛死于怀疑的功能衰竭.

结论:

摄入Indigofera cryptantha被强烈认为是导致南非牛的色素和潜在的毒性.
植物的印地卡含量会被代谢成硫酸,导致尿液颜色变暗,可能导致脏损伤.
这是南非首次报告在牛群中出现I. cryptantha诱导的色素.

关键词:

牛群是牛群,牛群是牛群,牛群是牛群.印第哥是一种印第哥色.印地瓜 (Indigofera cryptantha) 是一种有着密码的植物.印度硫酸盐印度酸盐颜色尿症是什么颜色尿症通过UPLC-UV-qTOF/MS进行分析.

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