优化种植策略和扩大使用Pavlova sp的fucoxanthin生产规模
Chun-Yen Chen1, Ping-Yung Liu2, Yu-Han Chang2
1University Center for Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan; Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan 701, Taiwan.
Bioresource technology
|March 20, 2024
概括
这项研究优化了微藻的富可桑丁产量,识别了Pavlova sp. 作为一个高产品种. 大规模种植证明了这种抗氧化化合物的商业潜力.
科学领域:
- 海洋生物技术 海洋生物技术
- 自然产品化学 自然产品化学
- 物理学的生理学
背景情况:
- 富可丁是一种海洋类胡卜素,具有显著的抗氧化和抗癌特性.
- 微藻类是富可桑生产的可持续来源.
- 有效的提取和种植方法对于商业可行性至关重要.
研究的目的:
- 选海洋微藻,以获得高富可桑产量.
- 优化种植参数,以提高富可丁的生产.
- 为了评估使用Pavlova sp.的fucoxanthin生产的可扩展性.
主要方法:
- 对三种棕色海洋微藻菌株进行查:骨架菌 costatum,Chaetoceros gracilis和Pavlova sp.
- 优化培养介质,盐度,酸,注射剂大小,光强度和铁度.
- 在50L管状光生物反应器中进行大规模培养.
主要成果:
- 帕夫洛娃 sp. 在这里. 显示了最高的富可桑含量 (27.91 mg/g) 和生产力 (1.16 mg/L·day).
- 优化条件导致富可桑的最大生产率为7.89 mg/L·day.
- 大规模种植实现了生物质和富可丁的生产率,分别为70.7毫克/日和4.78毫克/日.
结论:
- 帕夫洛娃 sp. 在这里. 是一个有前途的微藻菌株用于富可桑的生产.
- 优化的种植策略显著提高了富可桑的产量.
- 开发的工艺显示了大型富可丁合成的商业潜力.
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