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Updated: Jun 30, 2025

The Determination of Protease Specificity in Mouse Tissue Extracts by MALDI-TOF Mass Spectrometry: Manipulating PH to Cause Specificity Changes
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使用机器学习策略识别和功能分析一种血清蛋白酶抑制剂

Heqian Zhang1, Yaxin Wu1, Yanran Zhu1

  • 1Center for Biological Science and Technology, Advanced Institute of Natural Sciences, Beijing Normal University, Zhuhai, Guangdong 519087, China.

International journal of biological macromolecules
|March 20, 2024
PubMed
概括

研究人员使用AI在Marsupenaeus japonicus中发现了28只蛇. 一种serpin,Mjserpin-1,显示出作为抗病毒和亡抑制剂的潜力,突出了AI.

关键词:
抗病毒药物 抗病毒药物亡抑制剂是一种亡抑制剂.大型蛋白质语言模型分子对接是分子对接.血清蛋白酶抑制剂 血清蛋白酶抑制剂

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Protein-protein Interfaces02:04

Protein-protein Interfaces

Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
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