富含多烯的食用粉纳米材料对抗氧化能力和肠道微生物群的影响
Wenzhi Lei1, Maodong Qi2, Pei Tan1
1College of Food Science and Engineering, Northwest A&F University, 712100 Yangling, Shaanxi, People's Republic of China.
International journal of biological macromolecules
|March 20, 2024
概括
粉纳米颗粒 (SNPs) 有效地结合果果聚醇 (P-SNPs). 这些PSNP具有抗氧化功效,通过增加有益细菌和短链脂肪酸 (SCFA) 来促进肠道健康,并且在体内无毒.
科学领域:
- 食品科学与技术 食品科学与技术
- 纳米技术 纳米技术
- 营养科学 营养科学
背景情况:
- 来自农业副产品的多,如果果汁,具有潜在的健康益处.
- 粉纳米颗粒 (SNP) 为生物活性化合物提供了一种新的输送系统.
- 在SNP中封装聚醇可以提高它们的稳定性和生物可用性.
研究的目的:
- 研究聚醇粉纳米粒子复合体 (P-SNPs) 的体内抗氧化活性.
- 评估P-SNP对肠道微生物群的调节作用.
- 评估P-SNP对人类健康的安全性和有效性.
主要方法:
- 制备P-SNP通过对SNP吸附果残渣聚醇来制备P-SNP.
- 评估抗氧化能力的体内研究 (DPPH,ABTS,基清除).
- 毒理学评估 (肝脏,脏,肠道组织病理学) 和肠道微生物群分析 (SCFA 生产,细菌分析).
主要成果:
- P-SNP表现出显著的自由基清除活动.
- 在体内给予P-SNP时,没有显示出肝脏或肠道毒性.
- P-SNP增加了有益的肠道细菌 (乳杆菌,细菌) 和SCFA的产生,同时减少了致病性细菌.
- 在血清,肝脏和脏组织中观察到增强的抗氧化能力.
结论:
- P-SNP是一种安全有效的果果多的输送系统.
- P-SNP具有显著的抗氧化特性,并积极调节肠道微生物群的组成.
- 这种方法为利用农业副产品促进肠道健康和整体福祉提供了一个有希望的策略.
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