循环RNA作为癌症疫苗新抗原的来源

Yi Ren1,2, Thamizhanban Manoharan1,2, Beijia Liu1

  • 1Department of Pharmacy, National University of Singapore, Singapore.

概括

循环RNAs (circRNAs) 为结直肠癌 (CRC) 免疫疗法提供了一种新的新抗原来源,特别是在具有低突变负担的瘤中. 这项研究表明,来自circRNA的新表位细胞可以引起抗瘤T细胞反应并向癌细胞.

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