对早产母乳中胡卜素含量的纵向分析
Adi Uretzky1,2, Dror Mandel3,4, Anat Schwartz3,4
1Department of Neonatology, Tel Aviv Medical Center, Dana Dwek Children's Hospital, Tel Aviv, 6997801, Israel. adi.uretzky@gmail.com.
European journal of pediatrics
|March 21, 2024
概括
人母乳中胡卜素的含量在整个哺乳期都会发生变化,而黄蛋白和黄素在晚些时候变得更为突出. 婴儿血中胡卜素水平与母乳不同.
科学领域:
- 营养科学 营养科学
- 新生儿科学 新生儿科学
- 生物化学 生化学
背景情况:
- 人母乳 (HM) 的成分对早产婴儿发育至关重要.
- 胡卜素,像黄蛋白一样,是具有抗氧化特性的重要微量营养素.
- HM类胡卜素的变化可能会影响婴儿健康结果,例如早产视网膜病变 (ROP).
研究的目的:
- 来自出生体重非常低至极低的早产婴儿的母亲的HM中胡卜素含量变化的特征.
- 调查这些婴儿中HM黄蛋白和ROP发生之间的关系.
主要方法:
- 从39名早产婴儿的母亲 (妊娠年龄24.2-29.6周) 收集了6周的HM样本 (n=184).
- 在HM和婴儿血 (n=21) 中测量了黄蛋白,紫素,β-胡卜素和柳科的度.
- 在ROP的母亲和非ROP的婴儿之间比较了胡卜素样本.婴儿.
主要成果:
- 随着哺乳期的持续时间,胡卜素度 (白蛋白,紫素,β-胡卜素,甘) 降低,在乳母乳中最高.
- 柳科和β-胡卜素在早期占主导地位,而黄蛋白和山丁在成熟的HM中增加.
- 在婴儿血中,与HM (28%) 相比,黄蛋白的比例更高 (58%).
- 在ROP的母亲和非ROP的婴儿之间,HM黄蛋白没有显著的差异.
结论:
- 人类母乳中的胡卜素含量是动态的,在不同母亲之间和整个哺乳期都会有所不同.
- 胡卜素的特征显著地从胆乳转移到成熟的牛奶.
- 婴儿血中胡卜素的分布不同于母乳中的分布.
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