在患有双主动脉的患者中,心室心律不整
Michael Ghannam1, Boldizsar Kovacs1, Jackson Liang1
1Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Journal of cardiovascular electrophysiology
|March 21, 2024
概括
双主动脉 (BAV) 患者经常经历来自附近的心室失常 (VA). 晚期加多增强 (LGE) 在心脏MRI上是常见的,表明痕组织可以触发这些心律失常.
科学领域:
- 心脏病学 心脏病学
- 遗传性心脏病是一种先天性心脏病.
- 心脏电生理学 心脏电生理学
背景情况:
- 双动脉 (BAV) 是最常见的先天性心脏缺陷.
- 在BAV患者中,心室失常症 (VA) 的患病率和特征尚不清楚.
研究的目的:
- 在BAV患者中对VA进行表征.
- 调查晚期加多增强心磁共振成像 (LGE-CMR) 在VA患者的BAV患者中的作用.
主要方法:
- 对19名接受VA切除的BAV患者的回顾性分析.
- 所有患者都接受了编程腹腔刺激和LGE-CMR (除了一个).
- 进行了VA映射和切除.
主要成果:
- 观察到频繁的早发性心室收缩 (PVCs) 和可诱导心室低心率 (VT).
- 晚期加多增强 (LGE) 在13名患者中存在,在诱导性静脉瘤患者中痕更大.
- 常常将VA映射到周膜区域,并且切除导致PVC负载显著减少,喷射分数得到改善.
结论:
- 在BAV患者中,心室心律不整常常起源于周膜区域.
- 在这些患者中,LGE是常见的,与可诱导静脉瘤相关,这表明它代表了心律失常的基质.
- 对BAV的次要心室重塑可能会导致LGE和VA.
关键词:
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