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Updated: Jun 30, 2025

Characterization of In Vitro Differentiation of Human Primary Keratinocytes by RNA-Seq Analysis
07:29

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Published on: May 16, 2020

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皮肤上生长因子受体的抑制导致DSP突变的皮细胞的细胞表型纠正

Daniela Andrei1, Jeroen Bremer1, Duco Kramer1

  • 1Department of Dermatology, Expertise Center for Blistering Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Experimental dermatology
|March 21, 2024
PubMed
概括

一种新的desmoplakin (DSP) 基因变异导致皮肤和心脏疾病. 在患者细胞中抑制表皮生长因子受体 (EGFR) 恢复了德斯莫普拉金功能,这表明了与DSP相关的疾病的潜在治疗策略.

关键词:
欧洲农业基金会 (EGFR) 是一个基金.这里是desmoplakin.这就是我们所说的desmosome.

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