Tween 20 添加对聚二甲基西洛干微通道中的电动运输的影响
Seyed Mojtaba Tabarhoseini1, Joseph Bentor1, Walter Johnson2
1Department of Mechanical Engineering, Clemson University, Clemson, South Carolina, USA.
Electrophoresis
|March 21, 2024
概括
将Tween 20添加到微流体设备中可以显著减少流体和粒子运动. 谨慎使用此表面活性剂,因为它会影响微通道中的电动运输和吞吐量.
科学领域:
- 表面化学 表面化学
- 微流体学 微流体学
- 电动运动学 电动运动学
背景情况:
- Tween 20通常用于微流体,以防止颗粒聚合.
- 它对流体和粒子电动传输的影响在很大程度上尚未研究.
研究的目的:
- 实验性研究Tween 20对微流体设备中的电动力学传输的影响.
- 量化Tween 20度对流体和粒子运动的影响.
主要方法:
- 实验是在聚甲基氧微通道中进行的.
- 该研究测量了粒子和细胞的电运动和电泳运动.
- 在缓冲溶液中测试了Tween 20的不同度.
主要成果:
- 0.1% 在20岁之间显著降低了电气体,电动力学和电泳学运动.
- 较高的Tween 20度进一步降低了流动性,但以较低的速度.
- 聚乙烯颗粒和酵母细胞在Tween 20的存在下表现出减少的移动性.
结论:
- 在微流体系统中,Tween 20显著改变了电动力学运输现象.
- 使用Tween 20可能会对流量和粒子/细胞吞吐量产生负面影响.
- 需要仔细考虑Tween 20度,以优化电动力学微设备.
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