考虑到益生菌对健康的风险
Xiangyi Liu1,2, Haiyi Zhao1,2, Aloysius Wong1,2,3,4
1Department of Biology, College of Science, Mathematics and Technology, Wenzhou-Kean University, 88 Daxue Road, Ouhai, Wenzhou, Zhejiang Province, 325060, China.
Heliyon
|March 21, 2024
概括
益生菌虽然有益,但可能导致感染,免疫问题,并传播抗生素耐药性. 这次审查强调了益生菌对健康的潜在风险,敦促进一步研究.
科学领域:
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
- 胃肠病学 胃肠病学
背景情况:
- 益生菌被广泛认为对健康有好处,但潜在的不良影响往往被忽视.
- 最近的研究表明,与益生菌使用相关的健康风险很大,需要对其应用进行重新评估.
- 目前的文献主要集中在益处上,掩盖了关键的安全信息.
研究的目的:
- 审查和突出最近关于益生菌对健康不利影响的科学证据.
- 巩固有关益生菌如何导致感染,免疫失调,代谢障碍和过敏反应的信息.
- 强调益生菌在促进抗菌素耐药性传播中的作用.
主要方法:
- 优先考虑在过去五年内发表的研究.
- 对证据的系统性审查,优先考虑临床和人体样本研究,其次是体内, in situ,体外和in silico模型.
- 综合了与机会性感染,免疫效应,代谢障碍,过敏反应和抗菌素耐药性相关的发现.
主要成果:
- 益生菌与机会性感染有关,无论是系统性还是局部性.
- 据报道,与益生菌消费有关的有害免疫效应,代谢障碍和过敏反应.
- 有证据表明,益生菌可以促进抗菌素耐药性的传播,从而引起公众健康的关注.
结论:
- 益生菌与几种重大健康风险有关,需要认真考虑.
- 消费者,食品科学家和医疗从业人员需要了解这些潜在的不良影响.
- 进一步的研究对于澄清和减轻与益生菌使用相关的风险至关重要.
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