与SARS-Cov-2感染有关的心血管疾病和抑郁症之间的相互作用. 共同的机制,共同的症状
Ana Gonjilashvili1, Sophio Tatishvili1
1New Vision University, Tbilisi, Georgia.
概括
冠状病毒疾病19 (COVID-19) 疫情导致了心血管问题和心理健康问题. 这些情况,包括长期的COVID症状,是相互关联的,需要多学科的护理.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 精神病学是一个精神病学.
- 遗传学 是一个遗传学.
背景情况:
- 2020年宣布的冠状病毒疾病19 (COVID-19) 流行病呈现了肺炎作为主要症状.
- 然而,COVID-19也与重大心血管病理有关,包括急性冠状动脉综合征 (ACS),心肌炎,心肌病和心律失常,导致发病率和死亡率增加.
- 压力,抑郁和焦虑等心理健康问题会对COVID-19相关心血管疾病的预后产生负面影响.
研究的目的:
- 探索COVID-19感染,心血管疾病和心理健康之间的复杂相互作用.
- 要突出这些机制,如超炎症和细胞外囊泡 (EV) 介导的涉及非编码微RNA (miRNA) 的通信,这些机制将这些条件联系起来.
- 强调长期COVID综合征中评估神经和精神症状的临床意义.
主要方法:
- 关于COVID-19,心血管疾病和心理健康的临床论文和研究的文献综述.
- 对连接病毒感染,心脏功能障碍和心理痛苦的病理生理机制的分析.
- 检查长期COVID综合征的临床表现,包括心血管和神经/精神症状.
主要成果:
- COVID-19 感染可以加速或加剧心血管疾病,影响患者的治疗结果.
- 精神健康并发症显著恶化了COVID-19相关心血管疾病的短期和长期预后.
- 长期COVID综合征包括影响心脏,大脑和神经/精神功能的广泛症状,包括POTS,脑雾和抑郁症.
结论:
- COVID-19,心血管疾病和抑郁症之间的关系是多方面的,涉及炎症,生活方式因素和通过EVs和miRNAs的分子通信.
- 长期COVID症状呈现出复杂的临床图像,其性质既是心脏的,也是神经/精神的.
- 对受这些相互关联的疾病影响的患者进行有效的管理需要采用全面的,多学科的方法.
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